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Background
Pridopidine, in development for Huntington's disease, may modulate aberrant l‐dopa‐induced effects including l‐dopa‐induced dyskinesia (LID).
Objective
This study investigated whether pridopidine could reduce LID in the MPTP macaque model of Parkinson's disease and characterized the observed behavioral effects in terms of receptor occupancy.
Methods
The pharmacokinetic profile and effects...
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