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Changes in expression of neurorepair and neuroregenerative factors were examined after transient cerebral ischemia in relation to the effects of tissue plasminogen activator (tPA) and the free radical scavenger edaravone. Physiological saline or edaravone was injected twice during 90min of transient middle cerebral artery occlusion (tMCAO) in rats, followed by the same saline or tPA at reperfusion...
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