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Background/Aims: The aim of this study is to evaluate the tolerance and effects of infliximab combined with steroids in severe alcoholic hepatitis (AH).Methods: Twenty patients with biopsy-proven severe AH (Maddrey's score>32) received prednisone 40mg/day for 28 days and either infliximab 5mg/kg IV (group A) or placebo (group B) at day 0. Histology, plasma interleukin-6 (IL-6) and interleukin-8...
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