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The development of a minimally invasive therapy for local targeting of adipose tissues could represent an attractive approach for treating obesity. Here, the development and successful application of a nanomedicine that uses α‐lactalbumin (α‐lac) nanomicelles (M) to encapsulate the known anti‐obesity agent capsaicin (Cap), which is delivered directly to adipose tissue via a microneedle patch (MP),...
In article number 2011130, Yuan Li and co‐workers present a minimally invasive anti‐obesity treatment system that supports local targeting of adipose tissues. The microneedles successfully deliver pepper sourced compound‐capsaicin (Cap) loaded a‐lactalbumin micelles into subcutaneous adipocytes, promoting the “burning” anti‐lipogenesis effect of fat cells by Cap. This delivery system selectively targets...
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