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Detrusor sphincter dyssynergia (DSD) causes impaired micturition and high intra-vesical pressure that leads to potentially life-threatening urological complications. Botulinum toxin A (BTX-A) is an inhibitor of acetylcholine release at the neuromuscular junction, which can decrease muscle contractility. It has been used successfully in the treatment of focal dystonia and spasticity of skeletal muscles...
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