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Mechanical stress has an important effect on tendon‐to‐bone healing. The purpose of the present study was to compare tendon‐to‐bone healing in animals exposed to either tendon unloading (botulinum toxin injection) or excessive loading (treadmill running) in a murine rotator cuff repair model. Forty‐eight C57BL/6 mice underwent unilateral supraspinatus tendon detachment and repair. Mice in the unloaded...
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