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Morphine addiction is known as a serious social problem. Medial prefrontal cortex (mPFC) and ventral tegmental area (VTA) are two important sites of the brain that contribute to this type of addiction, and a complicated relation exists in between. In addition, neurotransmitters like glutamate and γ--Amino Butyric Acid (GABA) play an important role in the formation of these relations. Thus, the present...
Previous studies have indicated an association between diabetes mellitus and impairments in synaptic plasticity in the hippocampus. However, it is not clear if the impairments of synapses are pre- or post-synaptic or both. The aim of this study was to evaluate the extracellular basal levels of glutamate and GABA at dentate gyrus of anesthetized streptozotocin-induced diabetic rats, after 12 weeks...
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