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RNA-dependent protein kinase (PKR) is crucial for the innate immune response, cell growth, proliferation, signal transduction and apoptosis. The activation process of PKR has been studied for many years and is still under debate. To obtain new insight into the mechanism of PKR activation, we solved the crystal structure of a latent mutant of the PKR kinase domain (PKR-KD) in the apo form at a resolution...
The family Carlemanniaceae in East Asia and tropical Asia, comprising two genera, Carlemannia and Silvianthus, are mainly distributed along the southern foot of the Himalaya Mountains and the western and southern interface of the Yunnan Plateau. The main reproductive process for Carlemannia tetragona was verified as self-pollination by the pollination experiments in this work. Germination rates for...
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