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IntroductionWhen investigating coagulation assays to measure the effect of infused prothrombin (FII) in in vivo coagulopathy models, we found that addition of FII, plasma‐derived human FII (pd‐hFII) or recombinant human FII (r‐hFII), to normal plasma resulted in a concentration‐dependent increase in prothrombin time (PT) initiated with Innovin®.
MethodsThe effect on PT by addition to plasma of either...
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