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The chemokine CCL27 attracts skin-homing T cells. CCL27 production by keratinocytes is enhanced in skin lesions from patients with atopic dermatitis or psoriasis vulgaris. It is suggested that prostaglandin E 2 (PGE 2 ) regulates skin inflammation.We examined the in vitro effects of PGE 2 on CCL27 production in human keratinocytes.Keratinocytes were incubated with TNF-α in...
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