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The formation of co-amorphous combination of drug-excipient has proved to be a powerful approach to increase the dissolution of poorly water-soluble drugs. In the present study, four novel co-amorphous combinations of β-azelnidipine (β-AZE) and maleic acid (MAL) with the molar ratio of 1:1 and 1:2 were prepared by neat powder grinding (NG) and solvent-assisted grinding (SG) procedures, respectively...
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