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The activity of SIRT1 is regulated by many chemical compounds, such as nicotinamide and resveratrol. Here, we probed the specific functions of nicotinamide and resveratrol on bovine adipocyte proliferation and differentiation and showed that inhibition of SIRT1 by nicotinamide increased the number of preadipocytes and expression of adipocyte markers. Resveratrol-induced SIRT1 activation significantly...
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