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In a recent investigation carried out on a panel of trimethoxybenzanilides, we showed that the formation of an intramolecular hydrogen bond is a key element for tuning P‐gp inhibitory activity. In this study, we designed new structurally simplified trimethoxy benzamides (5–17, Table ) with the aim to uncover the minimal molecular requirements needed for P‐gp inhibition. The new prepared smaller‐sized...
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