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Aims
Insular cortex (IC) is involved in processing the information of pain. The aim of this study was to investigate roles and mechanisms of P2X7 receptors (P2X7Rs) in IC in development of visceral hypersensitivity of adult rats with neonatal maternal deprivation (NMD).
Methods
Visceral hypersensitivity was quantified by abdominal withdrawal reflex threshold to colorectal distension (CRD). Expression...
AimsTo investigate whether electroacupuncture (EA) produced analgesic effect and whether nuclear factor kappa B (NF‐κB) and cystathionine β synthase (CBS) involved in EA‐mediated analgesia in painful diabetic neuropathy in rats.
MethodsDiabetes was induced by an intraperitoneal injection of streptozotocin (STZ) in adult female rats. Mechanical pain threshold was measured by von Frey filaments. EA...
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