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Aims
To characterise the mutational profiles of poorly differentiated thyroid carcinoma (PDTC) and anaplastic thyroid carcinoma (ATC) and to identify markers with potential diagnostic, prognostic and therapeutic significance.
Methods and results
Targeted next‐generation sequencing with a panel of 18 thyroid carcinoma‐related genes was performed on tissue samples from 41 PDTC and 25 ATC patients...
AimsTo determine clinicopathological criteria and molecular markers helpful in distinguishing adrenocortical carcinomas (ACCs) from adrenocortical adenomas (ACAs).
Methods and resultsWe analysed retrospectively the clinical and pathological features of 50 adrenal cortical tumours, and tested the expression of miR483‐3p by in‐situ hybridization as well as the expression of IGF2 and Smad4 by immunohistochemistry...
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