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γ-Aminobutyric acid (GABA) synthesis in the brain is mediated by two major isoforms of glutamic acid decarboxylase, GAD 65 and GAD 67 . The contribution of these isoforms to GABA synthesis flux (V GAD ) is not known quantitatively. In the present study we compared V GAD in cortex of control and vigabatrin-treated rats under α-chloralose/70% nitrous oxide anesthesia,...
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