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Objective: To investigate how the mechanism of adipocyte–prostate cancer cell interaction affects the proliferation and differentiation of prostate cancer cells.
Methods: An androgen‐dependent cell line (LNCaP), two androgen‐independent cell lines (PC‐3, DU145), and mature adipocytes harvested from male Wistar rats were used. Cancer cells were co‐cultured with the isolated mature adipocytes in 3‐D...
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