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To investigate whether immunization with glutathione S-transferase (GST) and mutant toxic shock syndrome toxin 1 (mTSST-1) fusion protein can protect against Staphylococcus aureus infection, we purified a non-toxic mutant GST–mTSST-1 fusion protein. Mice were immunized with the GST–mTSST-1 plus alum adjuvant and then challenged with viable S. aureus. The results showed that the survival rate of GST–mTSST-1-immunized...
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