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This paper describes the design, modeling, fabrication and characterization MEMS Coulter counter that can detect and monitor the dynamic cell impedance changes in situ as a function of time after mixing isolated cell populations with different extracellular media within 0.3 s from the start of mixing. The novelty of this design is the use of multi-electrodes with vertical sidewalls to enable the measurements...
A novel MEMS Coulter counter for cell monitoring and detection is designed, fabricated and tested in this paper. Microfabrication is employed to form a multilayered sandwich structure consisting of an SU-8 microchannel on a glass substrate covered by a PDMS lid. The microchannel is further divided into a passive mixing region, a focusing region using negative dielectrophoretic forces and a measuring...
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