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In this study, we employed 1α‐hydroxylase knockout (1α‐(OH)ase−/−) mice to investigate the influence of 1,25‐dihydroxy vitamin D3 (1,25‐(OH)2D3) deficiency on the adult neurogenesis in the hippocampal dentate gyrus (DG). The numbers of both 24‐hr‐old BrdU+ cells and proliferating cell nuclear antigen positive cells in 8‐week‐old 1α‐(OH)ase−/− mice increased approximately twofold compared with wild‐type...
This study investigated the effects of progesterone (P4) on the production and survival of neurons in the hippocampal dentate gyrus of adult male mice. The administration of P4 (4 mg/kg) for 3 consecutive days beginning on the 0–2nd day after the first BrdU‐injection (BrdU‐D0–2) produced an approximately twofold increase in the number of 28‐ and 56‐day‐old BrdU+ cells in comparison to the controls,...
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