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In 2011, the Intractable Liver Diseases Study Group of Japan, established novel diagnostic criteria for “acute liver failure ”, and published the classification criteria for the etiologies of acute liver failure and late‐onset hepatic failure (LOHF) in 2013. According to this classification, HBV carriers showing acute hepatitis exacerbation were divided into 3 subgroups; asymptomatic or inactive HBV...
Aim: In Japan, the indication for liver transplantation in patients with acute liver failure (ALF) is currently determined according to the guideline published in 1996. However, its predictive accuracy has fallen in recent patients. Thus, we attempted to establish a new guideline.
Methods: The subjects were 1096 ALF patients enrolled in a nationwide survey. All patients showed a prothrombin time...
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