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Aims
To detect functional connectomes of akinetic‐rigid (AR) and tremor and compare their connection pattern.
Methods
Resting‐state functional MRI data of 78 drug‐naïve PD patients were enrolled to construct connectomes of AR and tremor via connectome‐based predictive modeling (CPM). The connectomes were further validated with 17 drug‐naïve patients to verify their replication.
Results
The connectomes...
Identifying a whole‐brain connectome‐based predictive model in drug‐naïve patients with Parkinson's disease and verifying its predictions on drug‐managed patients would be useful in determining the intrinsic functional underpinnings of motor impairment and establishing general brain–behavior associations. In this study, we constructed a predictive model from the resting‐state functional data of 47...
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