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Background
Protease‐activated receptor‐1 (PAR‐1) plays a major role in multiple disease processes, including colitis. Understanding the mechanisms coupling PAR‐1 to disease pathogenesis is complicated by the fact that PAR‐1 is broadly expressed across multiple cell types.
Objective
Determine the specific contributions of PAR‐1 expressed by macrophages and colonic enterocytes to infectious colitis...
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