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An efficient unprecedented Pd-catalyzed rapid 2-fluoroethoxylation of bromo-chalcones has been unveiled. The oxygen nucleophiles (fluoroalcohols) experience the rapid CO bond forming reaction for the first time, albeit the alcohols are known to be a weak nucleophile and have greater competing β–hydride elimination in the transition-metal-catalyzed (especially Pd and Cu) CO cross-coupling reaction...
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