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Extracellular signal‐regulated kinase 3 (ERK3) is a poorly characterized member of the mitogen‐activated protein (MAP) kinase family. Functional analysis of the ERK3 signaling pathway has been hampered by a lack of knowledge about the substrates and downstream effectors of the kinase. Here, we used large‐scale quantitative phosphoproteomics and targeted gene silencing to identify direct ERK3 substrates...
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