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Key points
Cholinergic projections from the pedunculopontine tegmental nucleus (PPTg) to the retrotrapezoid nucleus (RTN) are considered to be important for sleep–wake state‐dependent control of breathing.
The RTN also receives cholinergic input from the postinspiratory complex.
Stimulation of the PPTg increases respiratory output under control conditions but not when muscarinic receptors in the...
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