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Bacillus anthracis harbours two virulence plasmids, pXO1 (182kb) and pXO2 (95kb). Whereas pXO2 harbours the cap operon coding for the capsule, pXO1 contains the pag, lef, and cya genes coding for protective antigen, lethal, and oedema factors, respectively, as well as the atxA regulatory gene. These genes are located within a 44.8kb long pathogenicity island flanked by insertion sequences. Here, we...
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