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Capillary zone electrophoresis ultraviolet (CZE‐UV) has become increasingly popular for the charge heterogeneity determination of mAbs and vaccines. The ε‐aminocaproic acid (eACA) CZE‐UV method has been used as a rapid platform method. However, in the last years, several issues have been observed, for example, loss in electrophoretic resolution or baseline drifts. Evaluating the role of eACA on the...
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