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Two β1,3galactosyltransferases are detected in human colon cells: one corresponds to β3GalT1, the other (β3GalTx) is found to be different from any cloned β3GalT since in vitro it utilizes GlcNAc very efficiently under specific reaction conditions. Expression of β3GalT1 transcript is high in normal colon mucosa and control neuroectodermal cells, which do not express sialyl-Lewis a antigen, and low...
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