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Host immune response plays a critical role in disease manifestation and severity. In article number 2006123, Win Sen Kuan, Jongyoon Han, and co‐workers present a whole blood biophysical immune response profiling tool using deterministic lateral displacement microfluidics. The speed and accuracy of immune response stratification demonstrated in an emergency department has a clear impact in enabling...
Disease manifestation and severity from acute infections are often due to hyper‐aggressive host immune responses which change within minutes. Current methods for early diagnosis of infections focus on detecting low abundance pathogens, which are time‐consuming, of low sensitivity, and do not reflect the severity of the pathophysiology appropriately. The approach here focuses on profiling the rapidly...
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