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The modulation of the startle response (SR) by threatening stimuli (fear‐potentiated startle; FPS) is a proposed endophenotype for disorders of the fearful‐fearlessness spectrum. FPS has failed to show evidence of heritability, raising concerns. However, metrics used to index FPS—and, importantly, other conditional phenotypes that are dependent on a baseline—may not be suitable for the approaches...
Callous-unemotional (CU) traits comprise the core symptoms of psychopathy, yet no study has estimated the heritability of CU traits in a community sample of children using an instrument designed solely to assess CU traits. The current study uses data from 339 twin pairs aged 9–14 to examine the reliability and heritability of the parent-report Inventory of Callous-unemotional Traits (ICU) at two assessments...
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