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Aims
Solitary fibrous tumours (SFTs) are fibroblastic mesenchymal tumours with a 10–30% metastatic rate. Several risk models have been proposed for extrameningeal SFT, but they have not been evaluated in direct comparison with each other. The aim of this study is to compare the utility of published risk models in a multi‐institutional SFT cohort.
Methods and results
Clinicopathological data were...
Aims
TERT promoter mutations have been reported in 22% of solitary fibrous tumours (SFT) and have been associated with poor outcomes. We performed testing for TERT hot‐spot mutations in a large series of SFT in order to confirm this finding and explore clinicopathological correlates of mutation status.
Methods and results
PCR for TERT hot‐spot mutations C250T and C228T was performed on DNA extracted...
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