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Fatty acids are a vital energy source in fish and are of significant importance to their physiological wellbeing. Amago salmon (Oncorhynchus masou ishikawae) transgenic for a growth hormone (GH) show both accelerated growth and altered fatty acid composition and content in liver tissues. In particular, they show a decrease in saturated fatty acids and monounsaturated fatty acids, and an increase in...
Myostatin (MSTN) functions as a negative regulator of skeletal muscle mass. In mammals, MSTN-deficient animals result in an increase of skeletal muscle mass with both hyperplasia and hypertrophy. A MSTN gene is highly conserved within the fish species, allowing speculation that MSTN-deficient fish could exhibit a double-muscled phenotype. Some strategies for blocking or knocking down MSTN in adult...
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