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ObjectiveThis study explored the association between the risk of carbamazepine (CBZ)–induced Stevens‐Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) and CBZ dose, dose‐adjusted concentration, and ABCB1,CYP3A4,EPHX1,FAS,SCN1A,MICA,andBAG6 polymorphisms in patients of Han ethnicity with epilepsy who were living in northeastern China.
Materials and methodsWe determined the genotypes of...
ObjectiveEpilepsy is a serious neural disease that affects around 50 million people all over the world. Although for the majority patients with epilepsy, seizures are well controlled by currently available antiepileptic drugs (AEDs), there are still >30% of patients suffered from medically refractory epilepsy and approximately 30–40% of all epileptic patients affected by numerous side effects and...
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