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Anaplastic lymphoma kinase (ALK)-positive non–small-cell lung cancer patients exhibited heterogeneous magnitude of response and duration time to criztotinib treatment. This study explored ALK variants and the percentage of ALK-positive cells using fluorescent in situ hybridization (FISH) on clinical efficacy of crizotinib.A total of 120 patients with ALK rearrangement who were treated with criztotinib...
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