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While many dye binding aptamers have been reported, most of them were for light‐up aptamers that can significantly enhance the quantum yield of fluorophores. Sulforhodamine B (SRhB) was used as a target previously to select both DNA and RNA aptamers, and the DNA aptamer was a G‐quadruplex that can bind to a number of rhodamine analogs. In addition, the previous selections were performed by immobilizing...
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