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Objective
Insulin‐like growth factor 1 (IGF1) has anabolic and growth‐promoting effects, raising concerns regarding its potential to promote tumour growth. Circulating IGF1 is bound to binding proteins, which modulate bioavailability of IGF1. This study assessed the associations of IGF1 and its binding proteins 1 (IGFBP1) and 3 (IGFBP3) with cancer risk.
Design
A prospective cohort study of 4042...
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