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Background
Lipotoxicity plays an important role in the pathogenesis of β‐cell dysfunction. Glucagon‐like peptide‐1 (GLP‐1) is an incretin hormone that exerts beneficial effects on the number and function of islet β cells. However, the effect of lipotoxicity on GLP‐1 secretion is still unknown.
Methods
Twenty‐five patients who were newly diagnosed with diabetes were recruited from 400 subjects based...
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