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Objective: To evaluate the effect of magnetic nanoparticle containing 5-fluorouracil (5-FU) targeting in treating cholangiocarcinoma based on internal magnetic fields built inside the tumor. Methods: 32 nude mice of BABL/C bearing ectopic tumor were built by subcutaneouly injecting cholangiocarcinoma cell line QBC 939. Three weeks after tumor inoculation, the animal models were divided equally...
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