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The BRAFV600E mutation is reported in half of patients with Langerhans cell histiocytosis (LCH). This study investigated the detection of the BRAFV600E allele in circulating cell‐free (ccf) DNA in a paediatric LCH cohort. Children with BRAFV600E‐mutated LCH were investigated to detect ccf BRAFV600E at diagnosis (n = 48) and during follow‐up (n = 17) using a picolitre‐droplet digital PCR assay. At...
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