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An ongoing longitudinal study in Maracaibo, Venezuela, examined the interaction between apolipoprotein E (APOE) genotypes and Alzheimer's disease (AD) and vascular dementia (VD), evaluating age and gender as potential modifiers of risk. Overall, carriers of at least one 4 allele were at higher risk for AD, not for VD; however, the risk was significant only for subjects older than 65, and it increased...
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