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The distensibility of a blood vessel is a marker of atherosclerotic disease. Manual measurement of the distensibility on CTA images is a difficult task. In this paper we describe a method to automatically determine the distensibility of the carotid artery by locally analyzing the deformation field of a nonrigid registration of a series of ECG-gated CTA images. We evaluate two variants of the method,...
This article studies the possibility of detecting dementia in an early stage, using nonrigid registration of MR brain scans in combination with dissimilarity-based pattern recognition techniques. Instead of focussing on the shape of a single brain structure, we take into account the shape differences within the entire brain. Imaging data was obtained from a longitudinal, population based study of...
A popular technique for nonrigid registration of medical images is based on the maximization of their mutual information, in combination with a deformation field parameterized by cubic B-splines. The coordinate mapping that relates the two images is found using an iterative optimization procedure. This work compares the performance of eight optimization methods: gradient descent (with two different...
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