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Objectives
CREBBP alterations are associated with many diseases including leukaemia. However, CREBBP expression and its clinical relevance in paediatric acute lymphoblastic leukaemia have not been elucidated.
Methods
We studied CREBBP mRNA expression in 349 patients treated with either the BCH‐2003 or CCLG‐2008 protocol. Using a receiver operating characteristic curve, patients were divided into...
ObjectivesTo study E2F3a expression and its clinical significance in children with acute lymphoblastic leukemia (ALL).
MethodsWe quantified E2F3a expression at diagnosis in 148 children with ALL by real‐time PCR. In the test cohort (n = 48), receiver operating characteristic (ROC) curve was used to find the best cut‐off point to divide the patients into E2F3a low‐ and high‐expression groups. The...
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