The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Point mutations in Ras oncogenes are routinely screened for diagnostics and treatment of tumors (especially in colorectal cancer). Here, we develop an optical approach based on direct SERS coupled with chemometrics for the study of the specific conformations that single‐point mutations impose on a relatively large fragment of the K‐Ras gene (141 nucleobases). Results obtained offer the unambiguous...
Die Diskriminierung von Einzelpunktmutationen in großen Fragmenten des K‐RAS‐Gens mittels eines optischen, auf direkter oberflächenverstärkter Raman‐Streuung basierenden und mit chemometrischen Methoden gekoppelten Ansatzes wird von R. A. Alvarez‐Puebla, L. Guerrini et al. in der Zuschrift auf S. 2421 vorgestellt. Die eindeutige Klassifizierung unterschiedlicher Mutationen liefert einen für die Diagnostik...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.