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PurposeThe water molecule exchange rates in a series of DyDOTA‐(amide)X chelates were fine‐tuned to maximize the effects of T2‐exchange line broadening and improve T2 contrast.
MethodsFour DyDOTA‐(amide)X chelates having a variable number of glycinate side‐arms were prepared and characterized as T2‐exchange agents. The nonexchanging DyTETA chelate was also used to measure the bulk water T2 reduction...
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