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γ-Aminobutyric acid (GABA) is a neurotransmitter found in both the central and the peripheral nervous systems including the gastrointestinal tract. The aims of the present studies were to examine mechanisms by which GABA exerts gastroprotective effects against ethanol- and water-restraint stress (WRS)–induced gastric mucosal injury in the rat. GABA, administered intragastrically (400 mg/kg), induced...
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