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Minor histocompatibility antigen HA‐1‐specific cytotoxic lymphocyte (CTL) clones have apparent anti‐leukaemic efficacy, and the AML/ETO gene is a special fusion gene in leukaemic cells. Thus, we hypothesised that a vaccine targeting HA‐1 and AML/ETO could stimulate NK cells to target leukaemia cells. Furthermore, we packaged the vaccine using attenuated Salmonella to enhance its immuno‐activity. Expression...
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