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Recent developments in zinc enzyme models, in particular for carbonic anhydrase (CA), alkaline phosphatase (AP), and alcohol dehydrogenase (ADH) are presented. Although these models are simple zinc(II) complexes, they have helped to disclose the hitherto unsettled intrinsic properties of zinc (II)-dependent enzyme functions. The discussion emphasizes how H2O is activated by zinc(II) for the nucleophilic...
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