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Drugs, Driving and Traffic Safety gives a comprehensive overview of the effects of different medical conditions like neurological disorders, anxiety and depression and their pharmaceutical treatment on driving ability. In addition, the effects of alcohol and drugs of abuse are discussed. Leading experts present the different methodologies to examine effects of drugs on driving, and summarize the...
The research of winter depression (also known as winter type of seasonal affective disorder or SAD) has a unique history. Unlike other affective diseases, it has been discovered by the investigations in the field of chronobiology1,2 rather than throughout medical practice. Since the first systematic description of winter depression2 its biological basis has been extensively studied. A number of hypotheses...
Normal circadian rhythms are synchronized to a regular 24 hr environmental light/dark (L/D) cycle. Both suprachiasmatic nucleus (SCN) and melatonin are essential for this adaptation. Desynchronization of circadian rhythms as occurs in chronobiological disorders result in severe disturbances of sleep. The Circadian rhythm sleep Disorders (CRSDs) include delayed sleep phase syndrome (DSPS), Non 24 hr...
"A fascinating set of reviews, many of theoretical interest or practical import. 21st Century neurobiology will concentrate on modulating arousal states, as examined in this book. Further, the subject is amenable to thorough genetic analysis, this providing a useful output for modern molecular neurobiology." Donald W. Pfaff, Ph.D., The Rockefeller University "Sleep is an essential...
Pineal melatonin is synthesized and secreted in close association with the light/dark cycle. The temporal relationship between the nocturnal rise in melatonin secretion and the “opening of the sleep gate” (i.e., the increase in sleep propensity at the beginning of the night), coupled with the sleep-promoting effects of exogenous melatonin, support the view that endogenous melatonin is involved in...
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