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A series of sulfur-containing heterocyclic pyrazoline derivatives (C1–C18; D1–D9) have been synthesized and purified (all are new except one) to be screened for FabH inhibitory activity. Compound C14 showed the most potent biological activity against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Bacillus subtilis (MIC values: 1.56–3.13μg/mL), being comparable with the positive...
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